Everything You Need To Know Before Using Anadrol
Everything You Need To Know Before Using Anadrol

Everything You Need To Know Before Using Anadrol

Table of Contents

Using Anadrol

What is Anadrol?

Anadrol (often referred to as “A50” or “A-bombs” by athletes) was originally intended to assist those suffering from anemia, but it has subsequently been used extremely effectively to aid persons suffering from a variety of different ailments where weight loss is an issue. As a result, it is unquestionably an excellent agent for encouraging weight growth, increasing hunger, enhancing strength, and raising Red Blood Cell count. Aside from that, it has the same drawbacks as the majority of anabolic/androgenic steroids (AAS). Inhibiting your body’s natural hormone production (testosterone, estrogen, and so on), Anadrol 50 will have a bad impact on your blood lipid profile, may induce water retention, is known for creating headaches, and is very toxic to your liver, among other things (in fact, it has the worst reputation for hepatoxicity out of all steroids). Ironically, despite the fact that it is marketed by its original maker (Syntex) as having the ability to encourage weight gain via increased hunger, consuming too much of it may actually suppress your appetite!

It was under the trade name ‘Anapolon’ that Anadrol Oxymetholone first appeared on the market in the United Kingdom in 1961. Anadrol was marketed and FDA authorized during the 1960s in the United States as a powerful anabolic steroid for the treatment of anemia under the Syntex brand name. Syntex was the pharmaceutical firm that developed the Anadrol brand name. It was also recommended outside of the United States for those who were malnourished or had poor bone health. When other medications with less adverse effects were available, it fell out of favor and was eventually restricted to HIV/AIDS patients only.

Bodybuilders began taking the steroid during their golden years, and its popularity continued to grow during the 1990s and 2000s as the emphasis on mass and size grew more prevalent in the fitness industry. Today, it is still utilized by individuals who desire to gain a significant amount of muscle and strength in a short period of time by taking a supplement.

What does an Anadrol steroid do?

I believe that in order to acquire a thorough grasp of Anadrol 50’s effects on the body, we must first examine its benefits in comparison to its drawbacks. Anadrol 50 is an anabolic steroid. Anadrol is a DHT-derived chemical that is a 17-Alpha-Alkylated steroid, which means that it has had its carbon atoms at the 17th position changed in order to withstand oral intake. The majority of oral steroids are 17aa, which allows them to pass through your liver in a usable form more easily. That sounds fantastic, does not it? Let us make everything 17alpha-alkylate! As you may expect, there is a negative aspect to this.

Anadrol Adverse Reactions

Is Anadrol a good steroid?

In addition to making it possible for Anadrol to survive its initial trip through your liver, this 17aa change makes Anadrol an extremely demanding substance for your liver. How demanding is Anadrol, and how much weight can you expect to acquire as a result of using it? An Anadrol research was carried out for a period of 30 weeks, during which time a respectable number of adverse effects were observed, as you could anticipate. The notion that Anadrol may induce certain adverse effects has never really been contested in any way. But how successful was the medicine in the long run? First and first, it should be noted that this research was conducted on persons suffering from AIDS-related wasting, and they actually gained weight (8+kg), while the control group lost weight and saw higher death rates. Perhaps if you are participating in a research because you have wasting disease that is also a fatal condition, you do not want to be assigned to the control group. I believe this is the case. The weight growth in this research, on the other hand, peaked at 19-20 weeks, meaning that the remaining 10 weeks were not very fruitful in this regard. Given the toxicity of Anadrol 50, it is obvious that you would not want to use it for more than 20 weeks at a time. However, beyond that, any influence on weight and strength increases would be minor. The fact that this trial ran for such a long period of time (30 weeks) should have shown that side effects from Anadrol can be controlled and that the medicine may be administered without risk of adverse effects being experienced. People are often advised to restrict their consumption of Anadrol to no more than 4 weeks at a time. I am a little less cautious, and I believe you should be able to run Anadrol for at least six weeks.

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As previously indicated, however, the negative effects of this medication are not to be taken lightly; yet, they are readily prevented and manageable. One research even found that patients taking up to 100mgs of Oxymetholone had very minimal negative effects. Dan Duchaine, the author of the original UnderGround Steroid Handbook, claims to have taken it at levels of up to 150mgs per day. In certain quarters, the hepatotoxicity of Anadrol has been overstated, which is understandable. Regardless, my recommendation is to keep Anadrol usage to a maximum of 6 weeks, even if it is only to be on the safe side and avoid any negative side effects. Of course, I have personally used this medication for a considerably longer period of time.

Side effects of Anadrol

What are the side effects of Anadrol?


  • Pre-pubertal phallic enlargement with increased frequency of erection
  • Postpubertal inhibition of testicular function with testicular atrophy & azospermia
  • Impotency
  • Priapism
  • Epididymitis
  • Bladder irritability


  • Alopecia
  • Virilism
  • Menstrual irregularities
  • Male-like voice
  • Pediatrics
  • Premature closure of epiphyses
  • Depression
  • Excitation
  • Habituation
  • Insomnia
  • Acne
  • Gynecomastia
  • Change in libido
  • Diarrhea
  • Nausea
  • Vomiting
  • Electrolyte & water retention
  • Decr glucose tolerance
  • Incr LDL
  • Decr HDL
  • Bleeding in pts on anticoagulant tx
  • Cholestatic jaundice
  • Muscle cramps
  • Incr serum CPK
  • Incr creatine/creatinine excretion
  • Possibility of leukemia

How to use Anadrol


Male bodybuilders will often take 50-100mg of Anadrol each day for 4-8 weeks, depending on their goals.

For women who want to gain muscle, a safe and effective dosage is 12.5-25mg per day for a period of 4-6 weeks.

Because of Anadrol’s short half-life of 5-9 hours (21), it is recommended that dosages be divided and given on a regular basis throughout the day. Anadrol is normally packaged in 50mg dosages; thus, by cutting the tablets in half, you may administer 2-4 doses each day to yourself.

Important: Because anadrol tablets are fat-soluble, taking them with meals may reduce their bioavailability and hence reduce the effectiveness of the medication. As a consequence, taking Anadrol on an empty stomach will provide the optimum benefits.

Determining the Proper Dosage of Anadrol

What are your body fitness goals? It’s vital to examine this before contemplating Anadrol. Knowing your objectives can assist establish how much you need to take to reach them. Needless to say, your safety should always be in the forefront.

Online, you’ll discover numerous specialists expressing diverse viewpoints regarding the optimum dose of Anadrol. Most individuals begin with 50mg each day. But if you’re a real novice (never taken steroids and new to bodybuilding), then it’s preferable to start with 25mg.

Most tablets come in 50mg size, so you’ll have to split it in half. The goal is to enable your body to acclimatize to the medicine before boosting the amount. If you don’t detect any negative effects during the first two days, then raise it to 50mg.

If you do notice problems, such as elevated blood pressure and cholesterol levels, then lessen the dosage. Your weight increase will be slower, but it’s better to be cautious than sorry. Just continue improving your nutrition and workout to make up for it.

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The expert Anadrol user may take 50mg per day and achieve tremendous effects in as little as three to four weeks. Beginners that can tolerate this amount will also observe fast outcomes.

You’ll discover a select handful that take 75mg to 100mg daily, but the danger is significantly larger in these circumstances. Taking above 100mg everyday isn’t suggested. When you eat too much, it might diminish your appetite.

Administering Anadrol

Anadrol Injectables vs. Anadrol Tablets

The use of injectable Anadrol, according to some, means that you will not put any burden on your liver.

This, on the other hand, is incorrect. However, even though it will skip the liver upon entrance into the circulation, it will have to go via the liver once it leaves your body.

It is thought that injectable Anadrol is less hepatotoxic than oral Anadrol; yet, it still puts a burden on the liver’s ability to function properly.

Anadrol Injectables & Tablets

Because it is not broken down by the liver, injectable Anadrol provides you with a dosage that is 100 percent effective.

Because oral steroids are C-17 alpha alkylated, a very high proportion of the steroid’s active constituents are retained. Despite this, your body will not be able to use the whole dosage.

As a result, injectable Anadrol is more difficult to get than oral Anadrol, and there is no major advantage to taking injectable Anadrol over oral Anadrol, other than a modest reduction in liver strain, from using injectable Anadrol.

What is the best way to utilize Anadrol?

I would be prepared to incorporate Anadrol in a cycle that included injectable steroids, but I would not consider introducing any other 17aa substances. I would recommend starting any 6-week run of this compound at the beginning of a cycle as a way to “jumpstart” the process of seeing improvements as fast as possible. The rapid gains you will see while using Anadrol (up to a pound per day for the first two weeks is not unusual among users) will also be just as rapid to decrease after you stop using it. Unless, of course, you are merely utilizing it as a kicker while you wait for the effects of the other substances to take effect. I am going to go out on a limb here and say that using Anadrol as a “Jumpstart” is the most common way for athletes and bodybuilders to utilize this steroid today, and I am not wrong. I would also mention that this substance is very popular among strength athletes who do not have to worry about competing in weight classes (such as field athletes and strongmen), as well as powerlifters competing in the larger weight classes (such as Olympic lifters). Furthermore, it is worth noting that according to one study conducted by Schroder et al, Anadrol has the ability to lower serum SHBG (Sex Hormone Binding Globulin, which binds to your free test and renders it ineffective for anabolism, among other things) concentrations by 54.9 25.8 and 45 16.2 nmol/l in the 50- and 100-mg treatment groups, respectively, compared to the control group. This implies that when you take this medicine, there will be more free testosterone circulating throughout your body, which will, undoubtedly, cause some synergy when combined with other anabolic steroids. Because of the substantial quantities of weight and strength that may be acquired in a very short period of time when using this medication, I am sure this comes as no surprise to many.

The fact that Oxymetholone does not bind effectively to the androgen receptor (Relative Binding Affinity = too low to be measured) is another crucial and frequently overlooked aspect of this substance. This is the lowest relative binding affinity I have ever heard about. Essentially, what this tells me is that this steroid has a large number of non-receptor mediated effects, which makes it an extremely effective addition to ANY BULKING stack since it will not be fighting for receptor sites with the other steroids you are taking. Furthermore, as you would expect, it is a really terrible option for a cutting stack.

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Anadrol Cycles

What exactly is the Anadrol Cycle? How much should you put into it? This is really one of the most intriguing facts regarding Anadrol 50, and it is worth noting. See, most steroids generate what is known as a “dose respondent curve,” which is a fancy way of stating that the more you take, the more you get.

Among the few anabolic steroids, anadrol has a dosage response curve that flattens out fairly early. When you take 50mgs of Anadrol, you will see significant improvements in muscle mass. Take 100mgs of Anadrol and you will see even greater improvements in muscle mass. Although it has been shown that 100 mgs/day is just as effective for weight growth as 150 mgs/day, it has been discovered that it creates less negative effects and is less hazardous . I believe that the increase in benefit relative to cost from 50mgs to 100mgs is an acceptable increase, but this is not the case when the dose is more than 100mgs. To demonstrate how 50mg and 100mg of Oxymetholone genuinely affect strength when compared to one another, consider the following:

As you can see from the results of this research, increasing the dosage of Anadrol 50 by a factor of roughly two practically doubled the strength gains of the test participants. We can see that, when we look at changes in body composition as a result of Oxymetholone (see chart below), although the guys taking 100mgs (as opposed to the 50mgs group) experienced significantly more fat loss and significantly more Lean Body Mass gain, the differences were not as dramatic as the differences in strength gains between the two groups:

Anadrol Cycle

Even while I am not normally willing to speculate on the reasons why a certain medicine does or does not accomplish anything, in this particular instance I will. I am presuming that the larger dosages of Anadrol create enough appetite suppression (at least according to anecdotal evidence) to make eating a challenging task. It has also been shown to promote insulin resistance and glucose intolerance in certain people. Because of this, macronutrient absorption becomes less efficient, and gains may be reduced when the dose is more than 100mg/day, which may be a contributing reason to decreased growth. Unfortunately, Anadrol has a moderately negative impact on your body’s natural hormonal system, on par with most other oral steroids but not as bad as most injectables, and it is certainly not as detrimental to your lipid profile as many anabolic steroids are. Anadrol is also relatively safe for use in women.

Anadrol Cycle Examples

Starting with a modest dose is recommended for people who have never taken Anadrol before since they are unsure of what to anticipate. Their requirements may be met with 25 mg/day for four weeks. These individuals solely use Testosterone and Anadrol.

People who have previously taken Anadrol may raise the dose and cycle duration, but we suggest doing so in a more safe way to avoid side effects. It will be sufficient to take 50 mg every day for six weeks. Testosterone and Anadrol are sufficient, although some may want to supplement with a modest Deca dose.

Professionals: those who have previously taken Anadrol on a regular basis and who have also gained a significant amount of expertise with a variety of other potent steroids may opt for powerful stacks. They might take 100 mg every day for six weeks. Others will take 50 mg/day for eight weeks. However, taking 100 mg/day for 8 weeks is already likely to put you at risk of developing kidney failure. Anadrol is often stacked with Testosterone and Deca in the hands of professionals. The use of Trenbolone may be preferred by some. Exceptional specialists oversee the operation of all four of them!